Clinical and epidemiological analysis of the use of psychotropic drugs in children hospitalized in a national reference center

Published

2025-05-31

How to Cite

Fuentes Solano, A. A., Andrade González, R., & Giachetto, G. (2025). Clinical and epidemiological analysis of the use of psychotropic drugs in children hospitalized in a national reference center. Revista De Psiquiatría Infanto-Juvenil, 42(2), 20–31. https://doi.org/10.31766/revpsij.v42n2a3

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Section

Original article

Authors

DOI:

https://doi.org/10.31766/revpsij.v42n2a3

Keywords:

psychotropic drugs in children, autism spectrum disorder, attention deficit disorder, hyperactivity disorder

Abstract

Introduction: Given the problem of the increase in the prescription of psychotropic drugs, we sought to conduct a prospective study to establish the prevalence and clinical and epidemiological characteristics of the use of psychotropic drugs in paediatric patients. Objectives: To analyse the clinical and epidemiological characteristics of the use of psychotropic drugs in paediatric patients at the Pereira Rossel Hospital between the months of September and October 2023. Materials and methods: A descriptive, cross-sectional study was conducted by reviewing the electronic medical records and performing interviews. All children and adolescents between the ages of 2 and 14 who were admitted to moderate paediatric care wards and were receiving psychotropic drugs at the time of admission were included. Results: Within the classification of psychotropic drugs, 72% used antipsychotics. 47% of patients presented polypharmacy. The most used drug in monotherapy was Risperidone. Regarding polypharmacy, the most frequent combinations were antipsychotics with antidepressants. The most frequent reason for prescribing psychotropic drugs was disruptive disorders, impulse control disorders and behavioural disorders. Conclusion: Our study identified an increase in the use of psychotropic drugs in polytherapy and a need for proper monitoring following prescription. There was also a lack of indications for non-pharmacological treatments. Additional studies should be conducted to further explore these aspects and compare the effectiveness of the different approaches, in order to create a protocol for action for children and adolescents with mental health disorders.

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Author Biographies

Andrea Alexandra Fuentes Solano, Universidad de la República

Posgrado de Pediatría, Facultad de Medicina, Universidad de la República, Uruguay. 

Rodrigo Andrade González, Universidad de la República

Pediatra, Asistente de Pediatría, Facultad de Medicina, Universidad de la República, Uruguay. 

Gustavo Giachetto, Universidad de la República

Pediatra, Profesor de Clínica Pediátrica, Jefe de Servicio, Facultad de Medicina, Universidad de la República, Uruguay. 

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